A carregar...

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia

Hypoxia-inducible factor (HIF), a transcriptional complex conserved from Caenorhabditis elegans to vertebrates, plays a pivotal role in cellular adaptation to low oxygen availability. In normoxia, the HIF-α subunits are targeted for destruction by prolyl hydroxylation, a specific modification that p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Berra, Edurne, Benizri, Emmanuel, Ginouvès, Amandine, Volmat, Véronique, Roux, Danièle, Pouysségur, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC175782/
https://ncbi.nlm.nih.gov/pubmed/12912907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg392
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!