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Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300
The N-terminal BOX-I domain of p53 containing a docking site for the negative regulator MDM2 and the positive effector p300, harbours two recently identified phosphorylation sites at Thr18 or Ser20 whose affect on p300 is undefined. Biochemical assays demonstrate that although MDM2 binding is inhibi...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083821/ https://ncbi.nlm.nih.gov/pubmed/11258706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve025 |
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