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Viral Interferon Regulatory Factor 1 of Kaposi's Sarcoma-Associated Herpesvirus Binds to p53 and Represses p53-Dependent Transcription and Apoptosis

Kaposi's sarcoma-associated herpesvirus (KSHV) is related to the development of Kaposi's sarcoma. Open reading frame K9 of KSHV encodes viral interferon regulatory factor 1 (vIRF1), which functions as a repressor of interferon- and IRF1-mediated signal transduction. In addition, vIRF1 acts...

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Detalhes bibliográficos
Main Authors: Seo, Taegun, Park, Junsoo, Lee, Daeyoup, Hwang, Sun Gwan, Choe, Joonho
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114335/
https://ncbi.nlm.nih.gov/pubmed/11390621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.6193-6198.2001
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