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Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame 50 Represses p53-Induced Transcriptional Activity and Apoptosis

Kaposi's sarcoma-associated herpesvirus (KSHV) open reading frame 50 (ORF50) encodes a viral transcriptional activator which stimulates the transcription of viral early and late genes of KSHV. Here we show that ORF50 represses transcriptional activity of p53 and p53-induced apoptosis through in...

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Bibliografiske detaljer
Main Authors: Gwack, Yousang, Hwang, Seungmin, Byun, Hyewon, Lim, Chunghun, Kim, Jin Woo, Choi, Eui-Ju, Choe, Joonho
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114345/
https://ncbi.nlm.nih.gov/pubmed/11390631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.6245-6248.2001
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