Viral Interferon Regulatory Factor 1 of Kaposi's Sarcoma-Associated Herpesvirus Binds to p53 and Represses p53-Dependent Transcription and Apoptosis

Kaposi's sarcoma-associated herpesvirus (KSHV) is related to the development of Kaposi's sarcoma. Open reading frame K9 of KSHV encodes viral interferon regulatory factor 1 (vIRF1), which functions as a repressor of interferon- and IRF1-mediated signal transduction. In addition, vIRF1 acts as an onc...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Seo, Taegun, Park, Junsoo, Lee, Daeyoup, Hwang, Sun Gwan, Choe, Joonho
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114335/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.6193-6198.2001
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