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Curbing the nuclear activities of β-catenin: Control over Wnt target gene expression
Wnt molecules control numerous developmental processes by altering specific gene expression patterns, and deregulation of Wnt signaling can lead to cancer. Many Wnt factors employ β-catenin as a nuclear effector. Upon Wnt stimulation, β-catenin heterodimerizes with T-cell factor (TCF) DNA-binding pr...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083688/ https://ncbi.nlm.nih.gov/pubmed/11256619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd012 |
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