FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis

Wnt/β-catenin signaling is essential for stem cell regulation and tumorigenesis, but its molecular mechanisms are not fully understood. Here, we report that FoxM1 is a downstream component of Wnt signaling and is critical for β-catenin transcriptional function in tumor cells. Wnt3a increases the lev...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Nu, Wei, Ping, Gong, Aihua, Chiu, Wen-Tai, Lee, Hsueh-Te, Colman, Howard, Huang, He, Xue, Jianfei, Liu, Mingguang, Wang, Yong, Sawaya, Raymond, Xie, Keping, Yung, W.K. Alfred, Medema, René H., He, Xi, Huang, Suyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199318/
https://ncbi.nlm.nih.gov/pubmed/22014570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.08.016
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