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Wnt‐induced deubiquitination FoxM1 ensures nucleus β‐catenin transactivation

A key step of Wnt signaling activation is the recruitment of β‐catenin to the Wnt target‐gene promoter in the nucleus, but its mechanisms are largely unknown. Here, we identified FoxM1 as a novel target of Wnt signaling, which is essential for β‐catenin/TCF4 transactivation. GSK3 phosphorylates FoxM...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Chen, Yaohui, Li, Yu, Xue, Jianfei, Gong, Aihua, Yu, Guanzhen, Zhou, Aidong, Lin, Kangyu, Zhang, Sicong, Zhang, Nu, Gottardi, Cara J, Huang, Suyun
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801947/
https://ncbi.nlm.nih.gov/pubmed/26912724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592810
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