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Wnt‐induced deubiquitination FoxM1 ensures nucleus β‐catenin transactivation
A key step of Wnt signaling activation is the recruitment of β‐catenin to the Wnt target‐gene promoter in the nucleus, but its mechanisms are largely unknown. Here, we identified FoxM1 as a novel target of Wnt signaling, which is essential for β‐catenin/TCF4 transactivation. GSK3 phosphorylates FoxM...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801947/ https://ncbi.nlm.nih.gov/pubmed/26912724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592810 |
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