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Nonspecific Binding of Clostridium difficile Toxin A to Murine Immunoglobulins Occurs via the Fab Component

Clostridium difficile toxin A binds nonspecifically to a mouse monoclonal antibody (MAb) immunoglobulin G3 λ chain [IgG3(λ)], through the Fab component. This binding, which is retained even after boiling the MAb, is temperature dependent, with more toxin bound at 4 than 37°C (P = 0.0024). The nonspe...

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Bibliografiset tiedot
Päätekijät: Cooke, Deborah L., Borriello, S. Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC108153/
https://ncbi.nlm.nih.gov/pubmed/9573079
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