Nonspecific Binding of Clostridium difficile Toxin A to Murine Immunoglobulins Occurs via the Fab Component

Clostridium difficile toxin A binds nonspecifically to a mouse monoclonal antibody (MAb) immunoglobulin G3 λ chain [IgG3(λ)], through the Fab component. This binding, which is retained even after boiling the MAb, is temperature dependent, with more toxin bound at 4 than 37°C (P = 0.0024). The nonspe...

詳細記述

書誌詳細

出版年:	Infect Immun
主要な著者:	Cooke, Deborah L., Borriello, S. Peter
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1998
主題:	Molecular and Cellular Pathogenesis
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108153/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573079/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.5.1981-1984.1998
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