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Increased Epitope-Specific CD8(+) T Cells Prevent Murine Coronavirus Spread to the Spinal Cord and Subsequent Demyelination

CD8(+) T cells are important for clearance of neurotropic mouse hepatitis virus (MHV) strain A59, although their possible role in A59-induced demyelination is not well understood. We developed an adoptive-transfer model to more clearly elucidate the role of virus-specific CD8(+) T cells during the a...

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Autors principals: MacNamara, Katherine C., Chua, Ming Ming, Nelson, Peter T., Shen, Hao, Weiss, Susan R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075721/
https://ncbi.nlm.nih.gov/pubmed/15731231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3370-3381.2005
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