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Priming of CD8(+) T Cells during Central Nervous System Infection with a Murine Coronavirus Is Strain Dependent
Virus-specific CD8(+) T cells are critical for protection against neurotropic coronaviruses; however, central nervous system (CNS) infection with the recombinant JHM (RJHM) strain of mouse hepatitis virus (MHV) elicits a weak CD8(+) T-cell response in the brain and causes lethal encephalomyelitis. A...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447063/ https://ncbi.nlm.nih.gov/pubmed/18417581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00106-08 |
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