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Rare Homologous Gene Targeting in Histoplasma capsulatum: Disruption of the URA5(Hc) Gene by Allelic Replacement
URA5 genes encode orotidine-5′-monophosphate pyrophosphorylase (OMPpase), an enzyme involved in pyrimidine biosynthesis. We cloned the Histoplasma capsulatum URA5 gene (URA5(Hc)) by using a probe generated by PCR with inosine-rich primers based on relatively conserved sequences in OMPpases from othe...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Microbiology
1998
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC107550/ https://ncbi.nlm.nih.gov/pubmed/9748447 |
| Tagiau: |
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