Molecular Cloning of the Actinomycin Synthetase Gene Cluster from Streptomyces chrysomallus and Functional Heterologous Expression of the Gene Encoding Actinomycin Synthetase II

The actinomycin synthetases ACMS I, II, and III catalyze the assembly of the acyl peptide lactone precursor of actinomycin by a nonribosomal mechanism. We have cloned the genes of ACMS I (acmA) and ACMS II (acmB) by hybridization screening of a cosmid library of Streptomyces chrysomallus DNA with sy...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Schauwecker, Florian, Pfennig, Frank, Schröder, Werner, Keller, Ullrich
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107190/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.9.2468-2474.1998
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