Molecular Cloning of the Actinomycin Synthetase Gene Cluster from Streptomyces chrysomallus and Functional Heterologous Expression of the Gene Encoding Actinomycin Synthetase II

The actinomycin synthetases ACMS I, II, and III catalyze the assembly of the acyl peptide lactone precursor of actinomycin by a nonribosomal mechanism. We have cloned the genes of ACMS I (acmA) and ACMS II (acmB) by hybridization screening of a cosmid library of Streptomyces chrysomallus DNA with sy...

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Détails bibliographiques

Publié dans:	J Bacteriol
Auteurs principaux:	Schauwecker, Florian, Pfennig, Frank, Schröder, Werner, Keller, Ullrich
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Genetics and Molecular Biology
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107190/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.9.2468-2474.1998
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