Molecular Cloning of the Actinomycin Synthetase Gene Cluster from Streptomyces chrysomallus and Functional Heterologous Expression of the Gene Encoding Actinomycin Synthetase II

The actinomycin synthetases ACMS I, II, and III catalyze the assembly of the acyl peptide lactone precursor of actinomycin by a nonribosomal mechanism. We have cloned the genes of ACMS I (acmA) and ACMS II (acmB) by hybridization screening of a cosmid library of Streptomyces chrysomallus DNA with sy...

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Bibliografiska uppgifter

I publikationen:	J Bacteriol
Huvudupphov:	Schauwecker, Florian, Pfennig, Frank, Schröder, Werner, Keller, Ullrich
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 1998
Ämnen:	Genetics and Molecular Biology
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107190/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.9.2468-2474.1998
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