Molecular Cloning of the Actinomycin Synthetase Gene Cluster from Streptomyces chrysomallus and Functional Heterologous Expression of the Gene Encoding Actinomycin Synthetase II

The actinomycin synthetases ACMS I, II, and III catalyze the assembly of the acyl peptide lactone precursor of actinomycin by a nonribosomal mechanism. We have cloned the genes of ACMS I (acmA) and ACMS II (acmB) by hybridization screening of a cosmid library of Streptomyces chrysomallus DNA with sy...

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Vydáno v:	J Bacteriol
Hlavní autoři:	Schauwecker, Florian, Pfennig, Frank, Schröder, Werner, Keller, Ullrich
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1998
Témata:	Genetics and Molecular Biology
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107190/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.9.2468-2474.1998
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