Inhibition of Flavivirus Infections by Antisense Oligomers Specifically Suppressing Viral Translation and RNA Replication

RNA elements within flavivirus genomes are potential targets for antiviral therapy. A panel of phosphorodiamidate morpholino oligomers (PMOs), whose sequences are complementary to RNA elements located in the 5′- and 3′-termini of the West Nile (WN) virus genome, were designed to anneal to important...

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Detalhes bibliográficos
Main Authors: Deas, Tia S., Binduga-Gajewska, Iwona, Tilgner, Mark, Ren, Ping, Stein, David A., Moulton, Hong M., Iversen, Patrick L., Kauffman, Elizabeth B., Kramer, Laura D., Shi, Pei-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069577/
https://ncbi.nlm.nih.gov/pubmed/15795246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.4599-4609.2005
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