Levofloxacin and Ciprofloxacin Decrease Procainamide and N-Acetylprocainamide Renal Clearances

Ten healthy adults participated in a randomized, crossover drug interaction study testing procainamide only, procainamide plus levofloxacin, and procainamide plus ciprofloxacin. During levofloxacin therapy, most procainamide and N-acetylprocainamide (NAPA) pharmacokinetic parameters, including decre...

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Detalhes bibliográficos
Main Authors: Bauer, Larry A., Black, Douglas J., Lill, Jennifer S., Garrison, Julie, Raisys, Vidmantas A., Hooton, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1068590/
https://ncbi.nlm.nih.gov/pubmed/15793163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1649-1651.2005
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