Influence of Renal Failure on Intestinal Clearance of Ciprofloxacin in Rats

Following intravenous doses, ciprofloxacin pharmacokinetics in control and nephrectomized rats were studied. There were no differences between control and nephrectomized rats for area under the concentration-time curve in plasma or biliary clearance. The intestinal clearance of ciprofloxacin was inc...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Dautrey, Sophie, Rabbaa, Lydia, Laouari, Denise, Lacour, Bernard, Carbon, Claude, Farinotti, Robert
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89180/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.678
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