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The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4(+)CD25(+ )T cells

It is now generally accepted that CD4(+)CD25(+ )T(reg )cells play a major role in the prevention of autoimmunity and pathological immune responses. Their involvement in the pathogenesis of chronic arthritis is controversial, however, and so we examined their role in experimental antigen-induced arth...

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Detalhes bibliográficos
Main Authors: Frey, Oliver, Petrow, Peter K, Gajda, Mieczyslaw, Siegmund, Kerstin, Huehn, Jochen, Scheffold, Alexander, Hamann, Alf, Radbruch, Andreas, Bräuer, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065322/
https://ncbi.nlm.nih.gov/pubmed/15743476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1484
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