Developmental Stage, Phenotype, and Migration Distinguish Naive- and Effector/Memory-like CD4(+) Regulatory T Cells

Regulatory T cells (Tregs) fulfill a central role in immune regulation. We reported previously that the integrin α(E)β(7) discriminates distinct subsets of murine CD4(+) regulatory T cells. Use of this marker has now helped to unravel a fundamental dichotomy among regulatory T cells. α(E) (−)CD25(+)...

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Main Authors: Huehn, Jochen, Siegmund, Kerstin, Lehmann, Joachim C.U., Siewert, Christiane, Haubold, Uta, Feuerer, Markus, Debes, Gudrun F., Lauber, Joerg, Frey, Oliver, Przybylski, Grzegorz K., Niesner, Uwe, de la Rosa, Maurus, Schmidt, Christian A., Bräuer, Rolf, Buer, Jan, Scheffold, Alexander, Hamann, Alf
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211798/
https://ncbi.nlm.nih.gov/pubmed/14757740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031562
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