Induction of chronic destructive arthritis in SCID mice by arthritogenic fibroblast-like synoviocytes derived from mice with antigen-induced arthritis

BACKGROUND: Fibroblast-like synoviocytes (FLSs) from patients with rheumatoid arthritis (RA) are autonomously activated to maintain inflammation and joint destruction in co-transplantation models. To elucidate inducing mechanisms involved in this altered behavior, the arthritogenic potential of FLSs...

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Pubblicato in:Arthritis Res Ther
Autori principali: Frey, Oliver, Hückel, Marion, Gajda, Mieczyslaw, Petrow, Peter K., Bräuer, Rolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251107/
https://ncbi.nlm.nih.gov/pubmed/30466479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1720-y
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