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Differential role of RB in response to UV and IR damage

The retinoblastoma tumor suppressor (RB) is functionally inactivated in the majority of cancers and is a critical mediator of DNA damage checkpoints. Despite the critical importance of RB function in tumor suppression, the coordinate impact of RB loss on the response to environmental and therapeutic...

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Bibliographic Details
Main Authors: Bosco, Emily E., Knudsen, Erik S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065251/
https://ncbi.nlm.nih.gov/pubmed/15767283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki283
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