Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo

INTRODUCTION: Breast cancer is the leading cause of cancer death in women worldwide. Elevated expression of c-Myc is a frequent genetic abnormality seen in this malignancy. For a better understanding of its role in maintaining the malignant phenotype, we used RNA interference (RNAi) directed against...

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Main Authors: Wang, Yi-hua, Liu, Shuang, Zhang, Guo, Zhou, Cui-qi, Zhu, Hong-xia, Zhou, Xiao-bo, Quan, Lan-ping, Bai, Jin-feng, Xu, Ning-zhi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064129/
https://ncbi.nlm.nih.gov/pubmed/15743499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr975
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