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The knockdown of c-myc expression by RNAi inhibits cell proliferation in human colon cancer HT-29 cells in vitro and in vivo

We investigated the effects of RNA interference-mediated silencing of the c-myc gene on celluar proliferation and apoptosis in human colon cancer HT-29 cells in vitro and in vivo. A small interfering RNA (siRNA) targeting c-myc was designed, the DNA template was synthesized, and the siRNA was obtain...

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Podrobná bibliografie
Vydáno v:Cell Mol Biol Lett
Hlavní autoři: Zhang, Xiao, Ge, Yin-Lin, Tian, Run-Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: SP Versita 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275647/
https://ncbi.nlm.nih.gov/pubmed/19183865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-009-0001-9
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