Lentivirus-mediated RNAi knockdown of VEGFA in RKO colorectal cancer cells decreases tumor formation and growth in vitro and in vivo

Vascular endothelial growth factors (VEGF) play important roles in angiogenesis, vasculogenesis and endothelial cell growth. In endothelial cancers, secreted VEGF proteins induce endothelial cell proliferation, promote cell migration, inhibit apoptosis and induce blood vessel permeabilization. VEGFA...

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Bibliographic Details
Main Authors: Qiu, Jiang-Feng, Zhang, Zhi-Qi, Wang, Yong, You, Jun
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365827/
https://ncbi.nlm.nih.gov/pubmed/22670172
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