Mechanism of Efficient and Accurate Nucleotide Incorporation Opposite 7,8-Dihydro-8-Oxoguanine by Saccharomyces cerevisiae DNA Polymerase η

Most DNA polymerases incorporate nucleotides opposite template 7,8-dihydro-8-oxoguanine (8-oxoG) lesions with reduced efficiency and accuracy. DNA polymerase (Pol) η, which catalyzes the error-free replication of template thymine-thymine (TT) dimers, has the unique ability to accurately and efficien...

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Autores principales: Carlson, Karissa D., Washington, M. Todd
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Chromosome Structure and Dynamics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061627/
https://ncbi.nlm.nih.gov/pubmed/15743815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.6.2169-2176.2005
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