Fluoroquinolone Action against Mycobacteria: Effects of C-8 Substituents on Growth, Survival, and Resistance
Fluoroquinolones trap gyrase on DNA as bacteriostatic complexes from which lethal DNA breaks are released. Substituents at the C-8 position increase activities of N-1-cyclopropyl fluoroquinolones against several bacterial species. In the present study, a C-8-methoxyl group improved bacteriostatic ac...
Kaydedildi:
| Yayımlandı: | Antimicrob Agents Chemother |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1998
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797236/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.2978 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|