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A New Approach to In Vitro Comparisons of Antibiotics in Dynamic Models: Equivalent Area under the Curve/MIC Breakpoints and Equiefficient Doses of Trovafloxacin and Ciprofloxacin against Bacteria of Similar Susceptibilities

Time-kill studies, even those performed with in vitro dynamic models, often do not provide definitive comparisons of different antimicrobial agents. Also, they do not allow determinations of equiefficient doses or predictions of area under the concentration-time curve (AUC)/MIC breakpoints that migh...

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Wedi'i Gadw mewn:
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Firsov, Alexander A., Vostrov, Sergey N., Shevchenko, Alexander A., Portnoy, Yury A., Zinner, Stephen H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 1998
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797213/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.2841
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