A New Approach to In Vitro Comparisons of Antibiotics in Dynamic Models: Equivalent Area under the Curve/MIC Breakpoints and Equiefficient Doses of Trovafloxacin and Ciprofloxacin against Bacteria of Similar Susceptibilities

Time-kill studies, even those performed with in vitro dynamic models, often do not provide definitive comparisons of different antimicrobial agents. Also, they do not allow determinations of equiefficient doses or predictions of area under the concentration-time curve (AUC)/MIC breakpoints that migh...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Firsov, Alexander A., Vostrov, Sergey N., Shevchenko, Alexander A., Portnoy, Yury A., Zinner, Stephen H.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Assuntos:	Pharmacology
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105953/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797213/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.2841
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