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Use of Microsphere Technology for Targeted Delivery of Rifampin to Mycobacterium tuberculosis-Infected Macrophages

Microsphere technology was used to develop formulations of rifampin for targeted delivery to host macrophages. These formulations were prepared by using biocompatible polymeric excipients of lactide and glycolide copolymers. Release characteristics were examined in vitro and also in two monocytic ce...

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Main Authors: Barrow, Esther L. W., Winchester, Gary A., Staas, Jay K., Quenelle, Debra C., Barrow, William W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC105919/
https://ncbi.nlm.nih.gov/pubmed/9756777
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