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Efficacy of Microencapsulated Rifampin in Mycobacterium tuberculosis-Infected Mice

Rifampin is a first-line drug useful in the treatment of tuberculosis. By using biocompatible polymeric excipients of lactide and glycolide copolymers, two microsphere formulations were developed for targeted and sustained delivery of rifampin, with minimal dosing. A small-microsphere formulation, w...

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Autors principals: Quenelle, Debra C., Staas, Jay K., Winchester, Gary A., Barrow, Esther L. W., Barrow, William W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC89124/
https://ncbi.nlm.nih.gov/pubmed/10223927
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