Superior Efficacy of Liposomal Amphotericin B with Prolonged Circulation in Blood in the Treatment of Severe Candidiasis in Leukopenic Mice

In leukopenic mice with severe systemic candidiasis, single-dose treatment (5 mg of amphotericin B [AMB]/kg of body weight) with long-circulating polyethylene glycol-coated AMB liposomes (PEG-AMB-LIP) resulted in zero mortality and a significant reduction in the number of viable Candida albicans in...

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Xehetasun bibliografikoak
Egile Nagusiak: van Etten, Els W. M., Snijders, Susan V., van Vianen, Wim, Bakker-Woudenberg, Irma A. J. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 1998
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC105847/
https://ncbi.nlm.nih.gov/pubmed/9736577
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