Amphotericin B liposomes with prolonged circulation in blood: in vitro antifungal activity, toxicity, and efficacy in systemic candidiasis in leukopenic mice.

Pegylated amphotericin B (AmB) liposomes (PEG-AmB-LIP) were compared with laboratory-prepared nonpegylated AmB liposomes (AmB-LIP), a formulation with a lipid composition the same as that in AmBisome, as well as with industrially prepared AmBisome regarding their in vitro antifungal activities, toxi...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	van Etten, E W, ten Kate, M T, Stearne, L E, Bakker-Woudenberg, I A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162862/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8540697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.9.1954
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