A237T as a Modulating Mutation in Naturally Occurring Extended-Spectrum TEM-Type β-Lactamases
A TEM-1 β-lactamase derivative containing the single amino acid substitution A237T slightly increased (from 24 to 32 μg/ml) the cephalothin MIC for Escherichia coli RYC1000 but did not influence the activities of cefotaxime, ceftazidime, and aztreonam (MICs of 0.03, 0.12, and 0.06 μg/ml, respectivel...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Antimicrob Agents Chemother |
|---|---|
| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology (ASM)
1998
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105741/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9593123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.5.1042 |
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