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A237T as a Modulating Mutation in Naturally Occurring Extended-Spectrum TEM-Type β-Lactamases
A TEM-1 β-lactamase derivative containing the single amino acid substitution A237T slightly increased (from 24 to 32 μg/ml) the cephalothin MIC for Escherichia coli RYC1000 but did not influence the activities of cefotaxime, ceftazidime, and aztreonam (MICs of 0.03, 0.12, and 0.06 μg/ml, respectivel...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC105741/ https://ncbi.nlm.nih.gov/pubmed/9593123 |
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