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Gene Amplification in Leishmania tarentolae Selected for Resistance to Sodium Stibogluconate

Leishmania tarentolae promastigotes were selected step by step for resistance to sodium stibogluconate (Pentostam). Mutants resistant to antimony-containing drugs and cross-resistant to arsenite were therefore obtained. Amplification of one common locus was observed in several independent sodium sti...

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Detalhes bibliográficos
Main Authors: Haimeur, Anass, Ouellette, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105667/
https://ncbi.nlm.nih.gov/pubmed/9661005
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