Modulation of Gene Expression in Human Macrophages Treated with the Anti-Leishmania Pentavalent Antimonial Drug Sodium Stibogluconate

Within the mammalian host, Leishmania donovani is an obligatory intracellular protozoan parasite that resides and multiplies exclusively in the phagolysosomes of macrophages. Leishmania control relies primarily on chemotherapy, with the mainstay being pentavalent antimony (SbV) complexed to carbohyd...

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Autors principals: El Fadili, Karima, Imbeault, Michaël, Messier, Nadine, Roy, Gaétan, Gourbal, Benjamin, Bergeron, Marc, Tremblay, Michel J., Légaré, Danielle, Ouellette, Marc
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224789/
https://ncbi.nlm.nih.gov/pubmed/18070969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01183-07
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