Characterization of a Murine Monoclonal Antibody to Cryptococcus neoformans Polysaccharide That Is a Candidate for Human Therapeutic Studies

The murine monoclonal antibody (MAb) 18B7 [immunoglobulin G1(κ)] is in preclinical development for treatment of Cryptococcus neoformans infections. In anticipation of its use in humans, we defined the serological and biological properties of MAb 18B7 in detail. Structural comparison to the related p...

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Autores principales: Casadevall, Arturo, Cleare, Wendy, Feldmesser, Marta, Glatman-Freedman, Aharona, Goldman, David L., Kozel, Thomas R., Lendvai, Nikoletta, Mukherjee, Jean, Pirofski, Liise-anne, Rivera, Johanna, Rosas, Angel L., Scharff, Matthew D., Valadon, Philippe, Westin, Katherine, Zhong, Zhaojing
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Biologic Response Modifiers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC105619/
https://ncbi.nlm.nih.gov/pubmed/9624491
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