Characterization of a Murine Monoclonal Antibody to Cryptococcus neoformans Polysaccharide That Is a Candidate for Human Therapeutic Studies

The murine monoclonal antibody (MAb) 18B7 [immunoglobulin G1(κ)] is in preclinical development for treatment of Cryptococcus neoformans infections. In anticipation of its use in humans, we defined the serological and biological properties of MAb 18B7 in detail. Structural comparison to the related p...

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Main Authors: Casadevall, Arturo, Cleare, Wendy, Feldmesser, Marta, Glatman-Freedman, Aharona, Goldman, David L., Kozel, Thomas R., Lendvai, Nikoletta, Mukherjee, Jean, Pirofski, Liise-anne, Rivera, Johanna, Rosas, Angel L., Scharff, Matthew D., Valadon, Philippe, Westin, Katherine, Zhong, Zhaojing
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1998
主題:
Biologic Response Modifiers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC105619/
https://ncbi.nlm.nih.gov/pubmed/9624491
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