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Characterization of a Murine Monoclonal Antibody to Cryptococcus neoformans Polysaccharide That Is a Candidate for Human Therapeutic Studies

The murine monoclonal antibody (MAb) 18B7 [immunoglobulin G1(κ)] is in preclinical development for treatment of Cryptococcus neoformans infections. In anticipation of its use in humans, we defined the serological and biological properties of MAb 18B7 in detail. Structural comparison to the related p...

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Detalhes bibliográficos
Main Authors: Casadevall, Arturo, Cleare, Wendy, Feldmesser, Marta, Glatman-Freedman, Aharona, Goldman, David L., Kozel, Thomas R., Lendvai, Nikoletta, Mukherjee, Jean, Pirofski, Liise-anne, Rivera, Johanna, Rosas, Angel L., Scharff, Matthew D., Valadon, Philippe, Westin, Katherine, Zhong, Zhaojing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105619/
https://ncbi.nlm.nih.gov/pubmed/9624491
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