Characterization of a Murine Monoclonal Antibody to Cryptococcus neoformans Polysaccharide That Is a Candidate for Human Therapeutic Studies

The murine monoclonal antibody (MAb) 18B7 [immunoglobulin G1(κ)] is in preclinical development for treatment of Cryptococcus neoformans infections. In anticipation of its use in humans, we defined the serological and biological properties of MAb 18B7 in detail. Structural comparison to the related p...

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Main Authors: Casadevall, Arturo, Cleare, Wendy, Feldmesser, Marta, Glatman-Freedman, Aharona, Goldman, David L., Kozel, Thomas R., Lendvai, Nikoletta, Mukherjee, Jean, Pirofski, Liise-anne, Rivera, Johanna, Rosas, Angel L., Scharff, Matthew D., Valadon, Philippe, Westin, Katherine, Zhong, Zhaojing
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1998
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Biologic Response Modifiers
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC105619/
https://ncbi.nlm.nih.gov/pubmed/9624491
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