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Effect of Grapefruit Juice on Clarithromycin Pharmacokinetics

To investigate whether grapefruit juice inhibits the metabolism of clarithromycin, 12 healthy subjects were given water or grapefruit juice before and after a clarithromycin dose of 500 mg in a randomized crossover study. Administration of grapefruit juice increased the time to peak concentration of...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Cheng, Kit L., Nafziger, Anne N., Peloquin, Charles A., Amsden, Guy W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105569/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559810/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.927
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