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Comparison of Pharmacodynamics of Azithromycin and Erythromycin In Vitro and In Vivo

In this study, we determined the efficacy of various dosing regimens for erythromycin and azithromycin against four pneumococci with different susceptibilities to penicillin in an in vitro pharmacokinetic model and in a mouse peritonitis model. The MIC was 0.03 μg/ml, and the 50% effective doses (de...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: den Hollander, Jan G., Knudsen, Jenny D., Mouton, Johan W., Fuursted, Kurt, Frimodt-Møller, Niels, Verbrugh, Henri A., Espersen, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105417/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9527789/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.2.377
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