Comparison of Pharmacodynamics of Azithromycin and Erythromycin In Vitro and In Vivo

In this study, we determined the efficacy of various dosing regimens for erythromycin and azithromycin against four pneumococci with different susceptibilities to penicillin in an in vitro pharmacokinetic model and in a mouse peritonitis model. The MIC was 0.03 μg/ml, and the 50% effective doses (de...

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Библиографические подробности

Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	den Hollander, Jan G., Knudsen, Jenny D., Mouton, Johan W., Fuursted, Kurt, Frimodt-Møller, Niels, Verbrugh, Henri A., Espersen, Frank
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1998
Предметы:	Experimental Therapeutics
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9527789/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.2.377
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