Comparison of Pharmacodynamics of Azithromycin and Erythromycin In Vitro and In Vivo

In this study, we determined the efficacy of various dosing regimens for erythromycin and azithromycin against four pneumococci with different susceptibilities to penicillin in an in vitro pharmacokinetic model and in a mouse peritonitis model. The MIC was 0.03 μg/ml, and the 50% effective doses (de...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	den Hollander, Jan G., Knudsen, Jenny D., Mouton, Johan W., Fuursted, Kurt, Frimodt-Møller, Niels, Verbrugh, Henri A., Espersen, Frank
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9527789/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.2.377
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