Selection of Resistant Streptococcus pneumoniae during Penicillin Treatment In Vitro and in Three Animal Models

Pharmacokinetic (PK) and pharmacodynamic (PD) properties for the selection of resistant pneumococci were studied by using three strains of the same serotype (6B) for mixed-culture infection in time-kill experiments in vitro and in three different animal models, the mouse peritonitis, the mouse thigh...

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Detalhes bibliográficos
Main Authors: Knudsen, Jenny Dahl, Odenholt, Inga, Erlendsdottir, Helga, Gottfredsson, Magnus, Cars, Otto, Frimodt-Møller, Niels, Espersen, Frank, Kristinsson, Karl G., Gudmundsson, Sigurdur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166083/
https://ncbi.nlm.nih.gov/pubmed/12878511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2499-2506.2003
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