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Pharmacokinetics and Absolute Bioavailability of Oral Foscarnet in Human Immunodeficiency Virus-Seropositive Patients

The pharmacokinetics, absolute bioavailability, accumulation, and tolerability over 8 days of an oral formulation of foscarnet (90 mg/kg of body weight once daily [QD] [n = 6], 90 mg/kg twice daily [BID] [n = 6], and 180 mg/kg QD [n = 3]) were investigated in 15 asymptomatic, human immunodeficiency...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Noormohamed, Faruq H., Youle, Michael S., Higgs, Christopher J., Martin-Munley, Sarah, Gazzard, Brian G., Lant, Ariel F.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105403/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9527775/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.2.293
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