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A Rapid Method for Simultaneous Detection of Phenotypic Resistance to Inhibitors of Protease and Reverse Transcriptase in Recombinant Human Immunodeficiency Virus Type 1 Isolates from Patients Treated with Antiretroviral Drugs

Combination therapy with protease (PR) and reverse transcriptase (RT) inhibitors can efficiently suppress human immunodeficiency virus (HIV) replication, but the emergence of drug-resistant variants correlates strongly with therapeutic failure. Here we describe a new method for high-throughput analy...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Hertogs, Kurt, de Béthune, Marie-Pierre, Miller, Veronica, Ivens, Tania, Schel, Patricia, Van Cauwenberge, Anja, Van den Eynde, Christel, van Gerwen, Veerle, Azijn, Hilde, van Houtte, Margriet, Peeters, Frank, Staszewski, Schlomo, Conant, Marcus, Bloor, Stuart, Kemp, Sharon, Larder, Brendan, Pauwels, Rudi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105399/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9527771/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.2.269
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