Adenovirus Type 5 E4orf3 Protein Relieves p53 Inhibition by E1B-55-Kilodalton Protein
The E1B-55-kDa protein of adenovirus type 5 and the p53 tumor suppressor gene product form a complex that localizes to the cytoplasm, thereby downregulating p53’s transcriptional activity. The E4orf6 protein binds and relocalizes E1B-55-kDa, and the proteins act synergistically to inactivate p53. We...
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| Publicado no: | J Virol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.2253-2262.1999 |
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