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Rescue from Photoreceptor Degeneration in the rd Mouse by Human Immunodeficiency Virus Vector-Mediated Gene Transfer

Retinitis pigmentosa (RP) is the most common inherited retinal disease, in which photoreceptor cells degenerate, leading to blindness. Mutations in the rod photoreceptor cGMP phosphodiesterase β subunit (PDEβ) gene are found in patients with autosomal recessive RP as well as in the rd mouse. We have...

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Udgivet i:J Virol
Principais autores: Takahashi, Masayo, Miyoshi, Hiroyuki, Verma, Inder M., Gage, Fred H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104309/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438872/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7812-7816.1999
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