Rescue from Photoreceptor Degeneration in the rd Mouse by Human Immunodeficiency Virus Vector-Mediated Gene Transfer

Retinitis pigmentosa (RP) is the most common inherited retinal disease, in which photoreceptor cells degenerate, leading to blindness. Mutations in the rod photoreceptor cGMP phosphodiesterase β subunit (PDEβ) gene are found in patients with autosomal recessive RP as well as in the rd mouse. We have...

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Bibliografiske detaljer
Main Authors: Takahashi, Masayo, Miyoshi, Hiroyuki, Verma, Inder M., Gage, Fred H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC104309/
https://ncbi.nlm.nih.gov/pubmed/10438872
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